39 yrs old lady with migraine headache with aura since 20 yrs Headache worse in light ,sound ,motion Better by sleep,pressure ,and after vomiting Desire to press the head against something Oversensitive to all impressions Headache in sunshine Nausea and vomiting but with much retching Constipation since 2 months gaseous distention ,upper abdomen ,better by eructation Pressure in abdomen after eating Stool with frequent ineffectual urging with feeling as if some stool remained Cramps in calves Irritable ,even least ailment affects her greatly Agg morning and night,mental exertion Amel sleep, rest, pressure Patient was given Nux vomica 1M and gradually increased to Nuw vomica 10 M All the complaints better gradually.